Both enantiomers of the heterocyclic GABA analogue homo-b-proline (3-pyrrolidineacetic acid) were synthesized by a chemoenzymatic method involving the use of two enantiocomplementary enzymes in the disymmetric hydrolyses of 3-nitromethylglutaric acid diethyl ester
A convenient chemoenzymatic synthesis of (R)-(-) and (S)-(+)-homo-beta-proline
FELLUGA, FULVIA;GOMBAC, VALENTINA;PITACCO, GIULIANA;VALENTIN, ENNIO
2004-01-01
Abstract
Both enantiomers of the heterocyclic GABA analogue homo-b-proline (3-pyrrolidineacetic acid) were synthesized by a chemoenzymatic method involving the use of two enantiocomplementary enzymes in the disymmetric hydrolyses of 3-nitromethylglutaric acid diethyl esterFile in questo prodotto:
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