During the last 20 years, pharmaceutical industry and academic eforts have led to several structurally unrelated classes of non peptide cholecystokinin-1 receptor antagonista. Due to the lack of high resolution structure of CCK1-R and its peptide ligand, different strategies to design antagonists have been adopted.
TWENTY YEARS OF NON-PEPTIDE CCK1 RECEPTOR ANTAGONISTS: ALL THAT GLITTERS IS NOT GOLD
LASSIANI, LUCIA;VARNAVAS, ANTONIOS
2006-01-01
Abstract
During the last 20 years, pharmaceutical industry and academic eforts have led to several structurally unrelated classes of non peptide cholecystokinin-1 receptor antagonista. Due to the lack of high resolution structure of CCK1-R and its peptide ligand, different strategies to design antagonists have been adopted.File in questo prodotto:
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