Surface enhanced Raman scattering spectra of guanine, guanosine and 2′-deoxyguanosine adsorbed on gold colloidal nanoparticles were obtained. From the striking similarity of the SERS spectra of these compounds, it can be evidenced that guanosine and 2′-deoxyguanosine adsorb on gold nanoparticles through the guanine moiety. The molecular sites involved in the interaction with the gold surface are the same for the 3 compounds: the oxygen of the carbonilic group and the N7 atom. Guanine, guanosine and 2′-deoxyguanosine adsorb on the gold substrates with a tilted orientation with respect to the metal surface. SERS data were interpreted taking into account density functional theoretical (DFT) calculations of guanine.

SERS studies of the adsorption of guanine derivatives on gold colloidal nanoparticles

BONIFACIO, ALOIS;BIGOTTO, ADRIANO
2005-01-01

Abstract

Surface enhanced Raman scattering spectra of guanine, guanosine and 2′-deoxyguanosine adsorbed on gold colloidal nanoparticles were obtained. From the striking similarity of the SERS spectra of these compounds, it can be evidenced that guanosine and 2′-deoxyguanosine adsorb on gold nanoparticles through the guanine moiety. The molecular sites involved in the interaction with the gold surface are the same for the 3 compounds: the oxygen of the carbonilic group and the N7 atom. Guanine, guanosine and 2′-deoxyguanosine adsorb on the gold substrates with a tilted orientation with respect to the metal surface. SERS data were interpreted taking into account density functional theoretical (DFT) calculations of guanine.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/1916072
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