A supercritical antisolvent precipitation process was applied to recrystallize vitamin B6 from ethanol solution in CO2. By means of the PengRobinson equation of state (PR EoS), we performed preliminary studies to identify better operative conditions in terms of the organic solvent, pressure, temperature, and ability to carry a precipitate of the solute. This simulation was also considered to estimate the vitamin B6 particle size starting from supersaturation conditions.
Antisolvent Precipitation of Vitamin B6: A Thermodynamic Study
KIKIC, IRENEO;DE ZORDI, NICOLA;MONEGHINI, MARIAROSA;SOLINAS, DARIO
2011-01-01
Abstract
A supercritical antisolvent precipitation process was applied to recrystallize vitamin B6 from ethanol solution in CO2. By means of the PengRobinson equation of state (PR EoS), we performed preliminary studies to identify better operative conditions in terms of the organic solvent, pressure, temperature, and ability to carry a precipitate of the solute. This simulation was also considered to estimate the vitamin B6 particle size starting from supersaturation conditions.File in questo prodotto:
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