The synthesis of the first examples of calix[4]arene-based Fischer carbene complexes is reported here. Fischer carbene complex 2 is the key intermediate to reach uracil-like derivatives 3 and 4. X-ray and NMR studies revealed that the uracyl-like synthon gives rise to a supramolecular dimer. The organometallic calixarene complexes showed a promising cytotoxicity towards human tumor cell lines.
Installing tungsten Fischer carbene complexes into a calixarene framework
BRANCATELLI, GIOVANNA;GEREMIA, SILVANO;
2016-01-01
Abstract
The synthesis of the first examples of calix[4]arene-based Fischer carbene complexes is reported here. Fischer carbene complex 2 is the key intermediate to reach uracil-like derivatives 3 and 4. X-ray and NMR studies revealed that the uracyl-like synthon gives rise to a supramolecular dimer. The organometallic calixarene complexes showed a promising cytotoxicity towards human tumor cell lines.File in questo prodotto:
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