The DEFB1 gene, encoding for the constitutively expressed human β-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis.

Caries and Innate Immunity: DEFB1 Gene Polymorphisms and Caries Susceptibility in Genetic Isolates from North-Eastern Italy

BEVILACQUA, LORENZO;GASPARINI, PAOLO;DI LENARDA, Roberto;CROVELLA, SERGIO
2016-01-01

Abstract

The DEFB1 gene, encoding for the constitutively expressed human β-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis.
2016
https://www.karger.com/Article/Abstract/450965
File in questo prodotto:
File Dimensione Formato  
DEFB1_Caries_Research_def.pdf

Accesso chiuso

Tipologia: Documento in Versione Editoriale
Licenza: Digital Rights Management non definito
Dimensione 2.58 MB
Formato Adobe PDF
2.58 MB Adobe PDF   Visualizza/Apri   Richiedi una copia
Caries_Research_Supp_Mat_def.pdf

Accesso chiuso

Descrizione: Supplementary Material
Tipologia: Altro materiale allegato
Licenza: Digital Rights Management non definito
Dimensione 23.46 kB
Formato Adobe PDF
23.46 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2893991
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 18
  • ???jsp.display-item.citation.isi??? 16
social impact