Beta defensin-1 gene (DEFB1) polymorphisms are not associated with atopic dermatitis in children and adolescents from northeast Brazil (Recife, Pernambuco)

Atopic dermatitis (AD) is a common inflammatory skin disease resulting from the interplay between environmental, immunological and genetic factors. In our study, we investigated the role of three single nucleotide polymorphisms (SNPs) at 5'-UTR of DEFB1 gene, encoding for the human beta defensin-1, on the susceptibility to develop AD in a group of Brazilian children and adolescents.

Titolo: Beta defensin-1 gene (DEFB1) polymorphisms are not associated with atopic dermatitis in children and adolescents from northeast Brazil (Recife, Pernambuco)
Autori: 
SEGAT, LUDOVICA
ZANIN, VALENTINA
TREVISIOL, CHIARA
CROVELLA, SERGIO
mostra contributor esterni 
Data di pubblicazione: 2010
Rivista: 
INTERNATIONAL JOURNAL OF DERMATOLOGY  
Abstract: Atopic dermatitis (AD) is a common inflammatory skin disease resulting from the interplay between environmental, immunological and genetic factors. In our study, we investigated the role of three single nucleotide polymorphisms (SNPs) at 5'-UTR of DEFB1 gene, encoding for the human beta defensin-1, on the susceptibility to develop AD in a group of Brazilian children and adolescents.
Handle: http://hdl.handle.net/11368/2894056
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/j.1365-4632.2009.04343.x
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