Proceedings (senza ISBN) del Congresso “IV Encontro Brasileiro sobre Fluidos Supercriticos, EBFS 2001”, Salvador – Bahia (BR), 9-11 ottobre 2001. - The phase behavior of near- and supercritical solutions with beta-adrenoceptor blocking agents (atenolol, propranolol HCl, sotalol HCl) and one anti-arhythmic drug (verpamil HCl), organic solvents and CO2 are investigated in a batch GAS apparatus at 298.1 and 313.1 K and different kinds of phase splits are observed. For one system the continuous anti-solvent precipitation is performed and the different morphology of the precipitated material is discussed.
Continuous Drug Beta-Adrenoceptor Sblocking Agent Production by Antisolvent Precipitation / Alessi, Paolo; Kikic, Ireneo; Larsen, A.; Cortesi, Angelo; Fogar, Alessia. - STAMPA. - (2001), pp. 27-34.
Continuous Drug Beta-Adrenoceptor Sblocking Agent Production by Antisolvent Precipitation
ALESSI, PAOLO;KIKIC, IRENEO;CORTESI, ANGELO;FOGAR, ALESSIA
2001-01-01
Abstract
Proceedings (senza ISBN) del Congresso “IV Encontro Brasileiro sobre Fluidos Supercriticos, EBFS 2001”, Salvador – Bahia (BR), 9-11 ottobre 2001. - The phase behavior of near- and supercritical solutions with beta-adrenoceptor blocking agents (atenolol, propranolol HCl, sotalol HCl) and one anti-arhythmic drug (verpamil HCl), organic solvents and CO2 are investigated in a batch GAS apparatus at 298.1 and 313.1 K and different kinds of phase splits are observed. For one system the continuous anti-solvent precipitation is performed and the different morphology of the precipitated material is discussed.Pubblicazioni consigliate
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