Proceedings (senza ISBN) del Congresso “IV Encontro Brasileiro sobre Fluidos Supercriticos, EBFS 2001”, Salvador – Bahia (BR), 9-11 ottobre 2001. - The phase behavior of near- and supercritical solutions with beta-adrenoceptor blocking agents (atenolol, propranolol HCl, sotalol HCl) and one anti-arhythmic drug (verpamil HCl), organic solvents and CO2 are investigated in a batch GAS apparatus at 298.1 and 313.1 K and different kinds of phase splits are observed. For one system the continuous anti-solvent precipitation is performed and the different morphology of the precipitated material is discussed.

Continuous Drug Beta-Adrenoceptor Sblocking Agent Production by Antisolvent Precipitation

ALESSI, PAOLO;KIKIC, IRENEO;CORTESI, ANGELO;FOGAR, ALESSIA
2001-01-01

Abstract

Proceedings (senza ISBN) del Congresso “IV Encontro Brasileiro sobre Fluidos Supercriticos, EBFS 2001”, Salvador – Bahia (BR), 9-11 ottobre 2001. - The phase behavior of near- and supercritical solutions with beta-adrenoceptor blocking agents (atenolol, propranolol HCl, sotalol HCl) and one anti-arhythmic drug (verpamil HCl), organic solvents and CO2 are investigated in a batch GAS apparatus at 298.1 and 313.1 K and different kinds of phase splits are observed. For one system the continuous anti-solvent precipitation is performed and the different morphology of the precipitated material is discussed.
2001
Supercritical fluids; GAS technique; Precipitation; Pharmaceuticals
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2556429
 Avviso

Registrazione in corso di verifica.
La registrazione di questo prodotto non è ancora stata validata in ArTS.

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact