Anthocyanins are among the various bioactive components of wines to which health- promoting effects are ascribed. Their bioavailability is however very limited, as shown by post- absorption plasma concentration values of 10-9–10-8 M. The cardiovascular system is one of the main targets of anthocyanin bioactivity. The presence of the membrane transporter bilitranslocase (T.C. 2.A.65.1.1) in the vascular endothelium allows the transport of wine anthocyanins from the blood into the cells. Here anthocyanins can trigger further biological responses, ending with the release of nitric oxide, a powerful factor of cardiovascular protection.
Wine Pigments: From Your Cup to Your Cells / Passamonti, Sabina; Vanzo, A.; Tramer, Federica; Ziberna, Lovro; Vrhovsek, U.; Mattivi, F.. - In: JOURNAL OF WINE RESEARCH. - ISSN 0957-1264. - STAMPA. - 22:2(2011), pp. 143-145. ( Winehealth 2010 Abbazia di Rosazzo (Udine) 03-06.10.2010) [10.1080/09571264.2011.603243].
Wine Pigments: From Your Cup to Your Cells
PASSAMONTI, SABINA;TRAMER, FEDERICA;ZIBERNA, Lovro;
2011-01-01
Abstract
Anthocyanins are among the various bioactive components of wines to which health- promoting effects are ascribed. Their bioavailability is however very limited, as shown by post- absorption plasma concentration values of 10-9–10-8 M. The cardiovascular system is one of the main targets of anthocyanin bioactivity. The presence of the membrane transporter bilitranslocase (T.C. 2.A.65.1.1) in the vascular endothelium allows the transport of wine anthocyanins from the blood into the cells. Here anthocyanins can trigger further biological responses, ending with the release of nitric oxide, a powerful factor of cardiovascular protection.Pubblicazioni consigliate
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