Clinical evidence highlights the importance of limiting airway pressure during mechanical ventilation. In addition, experimental results suggest the importance of avoiding lung overdistension and cyclic end–expiratory airspace collapse and reexpansion, indicating that both phenomena promote mechanical damage an release of inflammatory mediator. In this context, transtracheal oxygen therapy and tracheal gas insufflation could have a role as adjuncts to mechanical ventilation.

Principles and practice of mechanical ventilation

LUCANGELO, UMBERTO
2013-01-01

Abstract

Clinical evidence highlights the importance of limiting airway pressure during mechanical ventilation. In addition, experimental results suggest the importance of avoiding lung overdistension and cyclic end–expiratory airspace collapse and reexpansion, indicating that both phenomena promote mechanical damage an release of inflammatory mediator. In this context, transtracheal oxygen therapy and tracheal gas insufflation could have a role as adjuncts to mechanical ventilation.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2765726
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