Short peptides are attractive building blocks for supramolecular biomaterials for their low-cost, scalability of production and purification, possibility to encode biological messages, and to be processed by enzymes to fine-tune their lifetime toward controlled biodegradation. Over the last few decades, great progress has been made in the understanding of these building blocks for their tailored design to a variety of biological applications. This chapter reviews the design strategies to achieve hydrogels that have been applied to address a variety of biomedical needs. As more knowledge has been gathered in the field, a higher complexity could be achieved, for instance to target subcellular organelles, specific cells, and even to stimulate the immune response. Overall, self-assembling short peptides are reaching their full potential and have opened the gates to new paradigms in therapy to realize futuristic medicine.

Chapter 10. Minimalistic Peptide Self-assembly into Supramolecular Biomaterials

Cringoli, M. C.;Fornasiero, P.;Marchesan, S.
2021-01-01

Abstract

Short peptides are attractive building blocks for supramolecular biomaterials for their low-cost, scalability of production and purification, possibility to encode biological messages, and to be processed by enzymes to fine-tune their lifetime toward controlled biodegradation. Over the last few decades, great progress has been made in the understanding of these building blocks for their tailored design to a variety of biological applications. This chapter reviews the design strategies to achieve hydrogels that have been applied to address a variety of biomedical needs. As more knowledge has been gathered in the field, a higher complexity could be achieved, for instance to target subcellular organelles, specific cells, and even to stimulate the immune response. Overall, self-assembling short peptides are reaching their full potential and have opened the gates to new paradigms in therapy to realize futuristic medicine.
2021
978-1-78801-757-2
File in questo prodotto:
File Dimensione Formato  
Chapter 10_Marchesan.pdf

Accesso chiuso

Tipologia: Documento in Versione Editoriale
Licenza: Copyright Editore
Dimensione 1.18 MB
Formato Adobe PDF
1.18 MB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2992031
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 3
  • ???jsp.display-item.citation.isi??? ND
social impact