An Unprecedented Catalytic Motif Revealed in The Model Structure of Amide Hydrolyzing Antibody 312D6.

Here we report the results of a docking analysis carried out on the homology model of the variable fragment (Fv) region of antibody 312d6. A novel catalytic motif based on an arginine dyad, unprecedented in antibody hydrolases, is identified by this study.



Titolo: An Unprecedented Catalytic Motif Revealed in The Model Structure of Amide Hydrolyzing Antibody 312D6.
Autori: 
BENEDETTI, FABIO
BERTI, FEDERICO
mostra contributor esterni 
Data di pubblicazione: 2004
Rivista: 
CHEMBIOCHEM  
Abstract: Here we report the results of a docking analysis carried out on the homology model of the variable fragment (Fv) region of antibody 312d6. A novel catalytic motif based on an arginine dyad, unprecedented in antibody hydrolases, is identified by this study.
Handle: http://hdl.handle.net/11368/1690089
Digital Object Identifier (DOI): http://dx.doi.org/10.1002/cbic.200300738
Appare nelle tipologie:1.1 Articolo in Rivista

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http://hdl.handle.net/11368/1690089
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