An Unprecedented Catalytic Motif Revealed in The Model Structure of Amide Hydrolyzing Antibody 312D6.

Here we report the results of a docking analysis carried out on the homology model of the variable fragment (Fv) region of antibody 312d6. A novel catalytic motif based on an arginine dyad, unprecedented in antibody hydrolases, is identified by this study.



Titolo: An Unprecedented Catalytic Motif Revealed in The Model Structure of Amide Hydrolyzing Antibody 312D6.
Autori: 
BENEDETTI, FABIO
BERTI, FEDERICO
mostra contributor esterni 
Data di pubblicazione: 2004
Rivista: 
CHEMBIOCHEM  
Abstract: Here we report the results of a docking analysis carried out on the homology model of the variable fragment (Fv) region of antibody 312d6. A novel catalytic motif based on an arginine dyad, unprecedented in antibody hydrolases, is identified by this study.
Handle: http://hdl.handle.net/11368/1690089
Digital Object Identifier (DOI): http://dx.doi.org/10.1002/cbic.200300738
Appare nelle tipologie:1.1 Articolo in Rivista

File in questo prodotto:
Non ci sono file associati a questo prodotto.
Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/11368/1690089
  • Citazioni
  • PubMed Central ND
  • Scopus
  • WOS

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
 
 
 
©2014 University of Trieste dove siamo Privacy
Piazzale Europa,1 34127 Trieste, Italia - Tel. +39 040.558.7111 - P.IVA 00211830328 - C.F. 80013890324 - P.E.C.: ateneo@pec.units.it
 Copyright © 2020