Penicillin amidase catalyses the synthesis of amide bond in very high yield (>98%), using equimolar concentrations of the amine and the phenylacetic components. In situ hydrated phosphates were employed for controlling the water activity in a benzene/water system (97:3 v/v), where the water is taken up by the salt with formation of the hydrated species.
CONTROL OF ENZYME HYDRATION IN PENICILLIN AMIDASE CATALYSED SYNTHESIS OF AMIDE BOND / Ebert, Cynthia; Gardossi, Lucia; Linda, Paolo. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 37:(1996), pp. 9377-9377. [10.1016/S0040-4039(97)82968-1]
CONTROL OF ENZYME HYDRATION IN PENICILLIN AMIDASE CATALYSED SYNTHESIS OF AMIDE BOND
EBERT, CYNTHIA;GARDOSSI, Lucia;LINDA, PAOLO
1996-01-01
Abstract
Penicillin amidase catalyses the synthesis of amide bond in very high yield (>98%), using equimolar concentrations of the amine and the phenylacetic components. In situ hydrated phosphates were employed for controlling the water activity in a benzene/water system (97:3 v/v), where the water is taken up by the salt with formation of the hydrated species.File in questo prodotto:
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