The synthesis of a novel hapten containing a 1,4-diamino-2,3-diolbutane core unit is described. The molecule contains four stereogenic centres and has been synthesised via a stereoselective route. The absolute stereochemistry of each stereogenic carbon atom has been assigned by nuclear Overhauser effect experiments carried out on a number of derivatives. (C) 2004 Elsevier Ltd. All rights reserved.
Stereoselective synthesis of a novel pseudopeptide hapten for the generation of hydrolytic catalytic antibodies / CHIVA RODRIGUEZ, A.; PICO RAMOS, A.; Hawkes, G. E.; Berti, Federico; Resmini, M.. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - STAMPA. - 15:(2004), pp. 1847-1855. [10.1016/j.tetasy.2004.05.005]
Stereoselective synthesis of a novel pseudopeptide hapten for the generation of hydrolytic catalytic antibodies
BERTI, FEDERICO;
2004-01-01
Abstract
The synthesis of a novel hapten containing a 1,4-diamino-2,3-diolbutane core unit is described. The molecule contains four stereogenic centres and has been synthesised via a stereoselective route. The absolute stereochemistry of each stereogenic carbon atom has been assigned by nuclear Overhauser effect experiments carried out on a number of derivatives. (C) 2004 Elsevier Ltd. All rights reserved.Pubblicazioni consigliate
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