The diversity of the genes encoding aminoglycoside-modifying enzymes and their association with class 1 integrons in three pan-European clones of Acinetobacter baumannii were investigated. The occurrence of identical resistance genes, gene combinations and class 1 integrons associated with these genes in clonally distinct strains indicated that horizontal gene transfer plays a major role in the dissemination of aminoglycoside resistance in A. baumannii.
Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones / Nemec, A; Dolzani, Lucilla; Brisse, S; VAN DEN BROEK, P; Dijkshoorn, L.. - In: JOURNAL OF MEDICAL MICROBIOLOGY. - ISSN 0022-2615. - STAMPA. - 53:(2004), pp. 1233-1240. [10.1099/jmm.0.45716-0]
Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones
DOLZANI, LUCILLA;
2004-01-01
Abstract
The diversity of the genes encoding aminoglycoside-modifying enzymes and their association with class 1 integrons in three pan-European clones of Acinetobacter baumannii were investigated. The occurrence of identical resistance genes, gene combinations and class 1 integrons associated with these genes in clonally distinct strains indicated that horizontal gene transfer plays a major role in the dissemination of aminoglycoside resistance in A. baumannii.Pubblicazioni consigliate
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