Fullerene derivatives have interesting biological activities that make them good candidates for applications in medicinal chemistry. However, the development of these applications is hampered by the fact that fullerene derivatives are insoluble in water and polar media. We present here a general method for the preparation of N-functionalized fulleropyrrolidines with solubilizing groups via 1,3-dipolar cycloaddition of azomethine ylides to C .



Titolo: Synthetic Approaches Towards The Preparation of Water-Soluble Fulleropyrrolidine
Autori: 
DA ROS, TATIANA
BOSI, Susanna
PRATO, MAURIZIO
mostra contributor esterni 
Data di pubblicazione: 2000
Rivista: 
CARBON  
Abstract: Fullerene derivatives have interesting biological activities that make them good candidates for applications in medicinal chemistry. However, the development of these applications is hampered by the fact that fullerene derivatives are insoluble in water and polar media. We present here a general method for the preparation of N-functionalized fulleropyrrolidines with solubilizing groups via 1,3-dipolar cycloaddition of azomethine ylides to C .
Handle: http://hdl.handle.net/11368/1693500
Appare nelle tipologie:1.1 Articolo in Rivista

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