Polydimethylsiloxanes (PDMS) are surfactants largely used in supercritical conditions for different applications. Polydimethylsiloxanes with relatively low molecular weight have been used; their solubility in supercritical carbon dioxide at different conditions has been determined. They can be successfully used for increasing the solubility of some drugs in supercritical carbon dioxide; moreover the use of PDMS for the production of controlled drug release products has been also evaluated.
Polydimethylsiloxanes in Supercritical Solvent Impregnation (SSI) of Polymers
ALESSI, PAOLO;KIKIC, IRENEO;CORTESI, ANGELO;MONEGHINI, MARIAROSA
2003-01-01
Abstract
Polydimethylsiloxanes (PDMS) are surfactants largely used in supercritical conditions for different applications. Polydimethylsiloxanes with relatively low molecular weight have been used; their solubility in supercritical carbon dioxide at different conditions has been determined. They can be successfully used for increasing the solubility of some drugs in supercritical carbon dioxide; moreover the use of PDMS for the production of controlled drug release products has been also evaluated.File in questo prodotto:
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