The present report shows that ammonium-functionalised CNTs (f-CNTs) are able to form stable complexes with plasmid DNA. It is also demonstrated that the same f-CNTs penetrate cell membranes and are uptaken by cells while exhibiting reduced cytotoxicity.
Functionalized carbon nanotubes for plasmid DNA gene delivery / D., Pantarotto; R., Singh; D., Mccarthy; M., Erhardt; J. P., Briand; Prato, Maurizio; K., Kostarelos; A., Bianco. - In: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION. - ISSN 1433-7851. - STAMPA. - 43:(2004), pp. 5242-5246. [10.1002/anie.200460437]
Functionalized carbon nanotubes for plasmid DNA gene delivery
PRATO, MAURIZIO;
2004-01-01
Abstract
The present report shows that ammonium-functionalised CNTs (f-CNTs) are able to form stable complexes with plasmid DNA. It is also demonstrated that the same f-CNTs penetrate cell membranes and are uptaken by cells while exhibiting reduced cytotoxicity.File in questo prodotto:
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