The interaction between the 1-47 N-terminus of the CCK1-R and the anthranilic acid based antagonists has been investigated by fluorescence spectroscopy. These antagonists interact with W39 of the N-terminal domain of the CCK1-R like that of the endogenous ligand CCK-8.
ANTHRANILIC ACID BASED CCK1 RECEPTOR ANTAGONISTS AND CCK-8 HAVE A COMMON STEP IN THEIR "RECEPTOR DESMODYNAMIC PROCESSES" / DE LUCA, S; Saviano, M; Lassiani, Lucia; Yannakopoulou, K; Stefanidou, P; Aloj, L; Morelli, G; Varnavas, Antonios. - In: JOURNAL OF MEDICINAL CHEMISTRY. - ISSN 0022-2623. - STAMPA. - 49:(2006), pp. 2456-2462. [10.1021/jm051050n]
ANTHRANILIC ACID BASED CCK1 RECEPTOR ANTAGONISTS AND CCK-8 HAVE A COMMON STEP IN THEIR "RECEPTOR DESMODYNAMIC PROCESSES"
LASSIANI, LUCIA;VARNAVAS, ANTONIOS
2006-01-01
Abstract
The interaction between the 1-47 N-terminus of the CCK1-R and the anthranilic acid based antagonists has been investigated by fluorescence spectroscopy. These antagonists interact with W39 of the N-terminal domain of the CCK1-R like that of the endogenous ligand CCK-8.File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
