Surface enhanced Raman scattering spectra of guanine, guanosine and 2′-deoxyguanosine adsorbed on gold colloidal nanoparticles were obtained. From the striking similarity of the SERS spectra of these compounds, it can be evidenced that guanosine and 2′-deoxyguanosine adsorb on gold nanoparticles through the guanine moiety. The molecular sites involved in the interaction with the gold surface are the same for the 3 compounds: the oxygen of the carbonilic group and the N7 atom. Guanine, guanosine and 2′-deoxyguanosine adsorb on the gold substrates with a tilted orientation with respect to the metal surface. SERS data were interpreted taking into account density functional theoretical (DFT) calculations of guanine.

SERS studies of the adsorption of guanine derivatives on gold colloidal nanoparticles

BONIFACIO, ALOIS;BIGOTTO, ADRIANO
2005-01-01

Abstract

Surface enhanced Raman scattering spectra of guanine, guanosine and 2′-deoxyguanosine adsorbed on gold colloidal nanoparticles were obtained. From the striking similarity of the SERS spectra of these compounds, it can be evidenced that guanosine and 2′-deoxyguanosine adsorb on gold nanoparticles through the guanine moiety. The molecular sites involved in the interaction with the gold surface are the same for the 3 compounds: the oxygen of the carbonilic group and the N7 atom. Guanine, guanosine and 2′-deoxyguanosine adsorb on the gold substrates with a tilted orientation with respect to the metal surface. SERS data were interpreted taking into account density functional theoretical (DFT) calculations of guanine.
File in questo prodotto:
File Dimensione Formato  
PCCP_2005.pdf

Accesso chiuso

Descrizione: file pdf dell'articolo
Tipologia: Documento in Versione Editoriale
Licenza: Digital Rights Management non definito
Dimensione 566 kB
Formato Adobe PDF
566 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/1916072
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 49
  • ???jsp.display-item.citation.isi??? 44
social impact