Enantioselective hydrolysis of methyl ester of (±)-C75 was successfully accomplished by means of Acylase I from Aspergillus to afford (2R,3S)-(+)-C75 with 96% e.e. The unreacted methyl ester was recovered with >99% e.e. This latter compound was either chemically or enzymatically hydrolyzed to furnish (2S,3R)-(–)-C75 with >99% e.e.
The first kinetic enzymatic resolution of methyl ester of C75 / Chakrabarty, Kuheli; Forzato, Cristina; Nitti, Patrizia; Pitacco, Giuliana; Valentin, Ennio. - In: LETTERS IN ORGANIC CHEMISTRY. - ISSN 1570-1786. - ELETTRONICO. - 7/2010:(2010), pp. 245-248. [10.2174/157017810791112405]
The first kinetic enzymatic resolution of methyl ester of C75
CHAKRABARTY, KUHELI;FORZATO, Cristina;NITTI, PATRIZIA;PITACCO, GIULIANA;VALENTIN, ENNIO
2010-01-01
Abstract
Enantioselective hydrolysis of methyl ester of (±)-C75 was successfully accomplished by means of Acylase I from Aspergillus to afford (2R,3S)-(+)-C75 with 96% e.e. The unreacted methyl ester was recovered with >99% e.e. This latter compound was either chemically or enzymatically hydrolyzed to furnish (2S,3R)-(–)-C75 with >99% e.e.File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
