Chemical reduction of diethyl 1-oxo-hexylsuccinate resulted in the formation of the corresponding cis and trans disubstituted y-butyrolactones. Both racemic diastereomers were resolved by means of lipolytic enzymes leading to the precursors of interesting natural products such as (-)-methylenolactocin and (-)phaseolinic acid

Asymmetric Resolution of Diasteroisomeric 4-Ethoxycarbonyl-5-pentyl-gamma-butyrolactones by Crude PLE-mediated Hydrolysis

DRIOLI, Sara;FELLUGA, FULVIA;FORZATO, Cristina;NITTI, PATRIZIA;PITACCO, GIULIANA;VALENTIN, ENNIO
1997

Abstract

Chemical reduction of diethyl 1-oxo-hexylsuccinate resulted in the formation of the corresponding cis and trans disubstituted y-butyrolactones. Both racemic diastereomers were resolved by means of lipolytic enzymes leading to the precursors of interesting natural products such as (-)-methylenolactocin and (-)phaseolinic acid
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11368/2309403
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