Chemical reduction of diethyl 1-oxo-hexylsuccinate resulted in the formation of the corresponding cis and trans disubstituted y-butyrolactones. Both racemic diastereomers were resolved by means of lipolytic enzymes leading to the precursors of interesting natural products such as (-)-methylenolactocin and (-)phaseolinic acid
Titolo: | Asymmetric Resolution of Diasteroisomeric 4-Ethoxycarbonyl-5-pentyl-gamma-butyrolactones by Crude PLE-mediated Hydrolysis |
Autori: | |
Data di pubblicazione: | 1997 |
Rivista: | |
Abstract: | Chemical reduction of diethyl 1-oxo-hexylsuccinate resulted in the formation of the corresponding cis and trans disubstituted y-butyrolactones. Both racemic diastereomers were resolved by means of lipolytic enzymes leading to the precursors of interesting natural products such as (-)-methylenolactocin and (-)phaseolinic acid |
Handle: | http://hdl.handle.net/11368/2309403 |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/S1381-1177(96)00046-X |
Appare nelle tipologie: | 1.1 Articolo in Rivista |
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