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EnglishThe synthesis of new benzylidenaminoguanidine compounds is described. Some of these compounds were tested for antihypertensive activity in conscious unrestrained spontaneously hypertensive rats. The compounds examined possess a significant antihypertensive activity, qualitatively different from that of clonidine. For the tested compounds, the absence of the transient rise in blood pressure, which appears immediately after administration of clonidine-like drugs, is noteworthy.
| Titolo: | Antihypertensive activity of arylidenaminoguanidine derivatives. |
| Autori: | |
| Data di pubblicazione: | 1986 |
| Rivista: | |
| Abstract: | The synthesis of new benzylidenaminoguanidine compounds is described. Some of these compounds were tested for antihypertensive activity in conscious unrestrained spontaneously hypertensive rats. The compounds examined possess a significant antihypertensive activity, qualitatively different from that of clonidine. For the tested compounds, the absence of the transient rise in blood pressure, which appears immediately after administration of clonidine-like drugs, is noteworthy. |
| Handle: | http://hdl.handle.net/11368/2635622 |
| Appare nelle tipologie: | 1.1 Articolo in Rivista |
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