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EnglishThe authors consider the clinical aspects of the natural history of HTLV-III/LAV infection. Then, they report on the clinical experience on AIDS and AIDS-related complex in the Veneto area. The most represented risk factor of the observed HTLV-III seropositive patients is intravenous drug abuse. 41 patients were asymptomatic, 91 patients had persistent generalized lymphoadenopathy with the presence or absence of constitutional symptoms (LAS/ARC), 9 patients were affected by "minor" opportunistic infections, 9 were affected by idiopathic thrombocytopenia and 7 were affected by full-blown AIDS. In this study the relationship between deterioration of cellular-mediated immunity and the clinical decline in HTLV III patients is confirmed by the decrease of circulating T4+ cells and of the T4+/T8+ ratio. High levels of seric IgG have been found in all patients, but only thrombocytopenic patients showed a statistically significant increased value.
| Titolo: | Aids e sindromi correlate: aspetti clinici ed esperienze cliniche nel Veneto |
| Autori: | |
| Data di pubblicazione: | 1986 |
| Rivista: | |
| Abstract: | The authors consider the clinical aspects of the natural history of HTLV-III/LAV infection. Then, they report on the clinical experience on AIDS and AIDS-related complex in the Veneto area. The most represented risk factor of the observed HTLV-III seropositive patients is intravenous drug abuse. 41 patients were asymptomatic, 91 patients had persistent generalized lymphoadenopathy with the presence or absence of constitutional symptoms (LAS/ARC), 9 patients were affected by "minor" opportunistic infections, 9 were affected by idiopathic thrombocytopenia and 7 were affected by full-blown AIDS. In this study the relationship between deterioration of cellular-mediated immunity and the clinical decline in HTLV III patients is confirmed by the decrease of circulating T4+ cells and of the T4+/T8+ ratio. High levels of seric IgG have been found in all patients, but only thrombocytopenic patients showed a statistically significant increased value. |
| Handle: | http://hdl.handle.net/11368/2715490 |
| Appare nelle tipologie: | 1.1 Articolo in Rivista |
