The rationale for a preformed combination of fosfomycin and amoxicillin is briefly discussed. These two antibacterial drugs block the peptidoglycal biosynthesis sequentially, thus exerting a true synergistic effect. On the other hand, there is no no synergism as far as toxicity is concerned. As the kinetics of the two molecules are different, further research on this topic is needed. This is especially true for renal failure patients

Impiego di un'associazione cofosfolattamina precostituita (fosfomicina + amoxicillina) nell'insufficienza renale

LUZZATI, ROBERTO
1985-01-01

Abstract

The rationale for a preformed combination of fosfomycin and amoxicillin is briefly discussed. These two antibacterial drugs block the peptidoglycal biosynthesis sequentially, thus exerting a true synergistic effect. On the other hand, there is no no synergism as far as toxicity is concerned. As the kinetics of the two molecules are different, further research on this topic is needed. This is especially true for renal failure patients
1985
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2715887
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