Anti-transglutaminase antibodies are the diagnostic marker of celiac disease, and are considered to be synthesized only by intestinal B-lymphocytes. During an infectious disease, these antibodies are transiently detected in serum. We show that these infection-triggered antibodies may not originate in the intestinal mucosa and are not an indication of celiac disease.

Serum Anti-Tissue Transglutaminase Antibodies Detected during Febrile Illness May Not Be Produced by the Intestinal Mucosa

DE LEO, LUIGINA;QUAGLIA, SARA;ZIBERNA, FABIANA;VATTA, SERENA;MASCHIO, MASSIMO;NOT, TARCISIO
2015

Abstract

Anti-transglutaminase antibodies are the diagnostic marker of celiac disease, and are considered to be synthesized only by intestinal B-lymphocytes. During an infectious disease, these antibodies are transiently detected in serum. We show that these infection-triggered antibodies may not originate in the intestinal mucosa and are not an indication of celiac disease.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11368/2832563
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