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EnglishIn order to evaluate the efficacy of topical cyclosporin in oral lichen planus, we have enrolled 12 patents, three males and nine females (age 45-69 years; mean age: 57 years). All patients were affected by lichen planus of oral mucose membrane; lichen planus was erosive in eight patients, reticulated in four. The disease was present from at least three years without a complete remission; other therapeutic regimens (corticosteroids, retinoids) were ended in failure. All these patients were symptomatic with various degrees of pain, burning and disability. Each patient had received cyclosporin in a formulation studied for systemic administration, containing 100 mg/ml (Sandimmun) as a mouthwash for eight weeks. The patients swished for five minutes and expectorated 5 ml of medication three times daily.
| Titolo: | Topical cyclosporine in oral lichen planus |
| Autori: | |
| Data di pubblicazione: | 1992 |
| Rivista: | |
| Abstract: | In order to evaluate the efficacy of topical cyclosporin in oral lichen planus, we have enrolled 12 patents, three males and nine females (age 45-69 years; mean age: 57 years). All patients were affected by lichen planus of oral mucose membrane; lichen planus was erosive in eight patients, reticulated in four. The disease was present from at least three years without a complete remission; other therapeutic regimens (corticosteroids, retinoids) were ended in failure. All these patients were symptomatic with various degrees of pain, burning and disability. Each patient had received cyclosporin in a formulation studied for systemic administration, containing 100 mg/ml (Sandimmun) as a mouthwash for eight weeks. The patients swished for five minutes and expectorated 5 ml of medication three times daily. |
| Handle: | http://hdl.handle.net/11368/2832844 |
| Appare nelle tipologie: | 1.5 Abstract in Rivista |
