ArTS Archivio della ricerca di Trieste
ArTS è il sistema di gestione integrata dei dati della ricerca adottato dall' Università degli Studi di Trieste
EnglishThe present manuscript addresses the description of binary systems of hyaluronan (HA) and alginate (Alg) in semi-concentrated solution. The two polysaccharides were completely miscible in the entire range of relative weight fraction explored at a total polymer concentration of up to 3 % (w/V). The rheological study encompassed steady flow and mechanical spectra for HA/Alg systems at different weight fractions with hyaluronan at different molecular weights. These extensive analyses allowed us to propose a model for the molecular arrangement in solution that envisages a mutual exclusion between the two polysaccharides even though a clear phase separation does not occur. This result may have profound implications when biomaterials based on the combination of alginate and hyaluronan are proposed in the field of biomedical materials.
| Titolo: | Rheology of mixed alginate-hyaluronan aqueous solutions |
| Autori: | |
| Data di pubblicazione: | 2015 |
| Rivista: | |
| Abstract: | The present manuscript addresses the description of binary systems of hyaluronan (HA) and alginate (Alg) in semi-concentrated solution. The two polysaccharides were completely miscible in the entire range of relative weight fraction explored at a total polymer concentration of up to 3 % (w/V). The rheological study encompassed steady flow and mechanical spectra for HA/Alg systems at different weight fractions with hyaluronan at different molecular weights. These extensive analyses allowed us to propose a model for the molecular arrangement in solution that envisages a mutual exclusion between the two polysaccharides even though a clear phase separation does not occur. This result may have profound implications when biomaterials based on the combination of alginate and hyaluronan are proposed in the field of biomedical materials. |
| Handle: | http://hdl.handle.net/11368/2840665 |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.ijbiomac.2015.04.009 |
| Appare nelle tipologie: | 1.1 Articolo in Rivista |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| Alginate - HA.pdf | Publisher-Version | Digital Rights Management non definito | Administrator Richiedi una copia | |
| Post print.pdf | Post-print |  | Open Access Visualizza/Apri |
