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EnglishThis mini-review examines key classes of short peptides capable of self-assembly into nanostructured hydrogels for biomaterial applications, with an eye for the current patent landscape. Systems reviewed are the ones based on heterochiral short peptides, N-protected peptides with aromatic moieties to induce π-π stacking (e.g., Fmoc, naphthalene), peptide amphiphiles displaying alkyl chains, amphiphilic peptides, beta-hairpin systems. Patents related to their more general use in cell culture or more tissue-specific applications are also briefly discussed. Concluding remarks on current and future developments will provide a perspective on the direction that this field is undertaking.
| Titolo: | Recent Patents on Peptide Self-Assembled Hydrogels as Nanostructured Biomaterials |
| Autori: | |
| Data di pubblicazione: | 2014 |
| Rivista: | |
| Abstract: | This mini-review examines key classes of short peptides capable of self-assembly into nanostructured hydrogels for biomaterial applications, with an eye for the current patent landscape. Systems reviewed are the ones based on heterochiral short peptides, N-protected peptides with aromatic moieties to induce π-π stacking (e.g., Fmoc, naphthalene), peptide amphiphiles displaying alkyl chains, amphiphilic peptides, beta-hairpin systems. Patents related to their more general use in cell culture or more tissue-specific applications are also briefly discussed. Concluding remarks on current and future developments will provide a perspective on the direction that this field is undertaking. |
| Handle: | http://hdl.handle.net/11368/2841349 |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.2174/1877912305666150213001402 |
| Appare nelle tipologie: | 1.1 Articolo in Rivista |
