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EnglishThe drug mass balance, performed on the entire human body, allows building up mathematical models able to account for the simultaneous processes of in vivo drug release kinetics and ADME steps (Absorption, Distribution, Metabolism and Elimination) that determine the drug pharmacokinetics (PK). As this approach holds whatever the administration route and the delivery system considered, it could play a paramount role in the development of personalized medicine.
| Titolo: | Mass balance: an old concept for the new challenges proposed by personalized medicine |
| Autori: | |
| Data di pubblicazione: | 2015 |
| Rivista: | |
| Abstract: | The drug mass balance, performed on the entire human body, allows building up mathematical models able to account for the simultaneous processes of in vivo drug release kinetics and ADME steps (Absorption, Distribution, Metabolism and Elimination) that determine the drug pharmacokinetics (PK). As this approach holds whatever the administration route and the delivery system considered, it could play a paramount role in the development of personalized medicine. |
| Handle: | http://hdl.handle.net/11368/2846645 |
| URL: | http://www.controlledreleasesociety.org/publications/Newsletter/Documents/v32i6.pdf |
| Appare nelle tipologie: | 1.1 Articolo in Rivista |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| Grassi M CRS 2015.pdf | pdf del contributo presentato al convegno | Altro materiale allegato | Digital Rights Management non definito | Administrator Richiedi una copia |
| v32i6-3.pdf | pdf editoriale | Documento in Versione Editoriale | Digital Rights Management non definito | Administrator Richiedi una copia |
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