A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a tripartite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.
Titolo: | The tripartite motif family identifies cell compartments |
Autori: | |
Data di pubblicazione: | 2001 |
Rivista: | |
Abstract: | A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a tripartite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments. |
Handle: | http://hdl.handle.net/11368/2847657 |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1093/emboj/20.9.2140 |
URL: | http://dx.medra.org/10.1093/emboj/20.9.2140 |
Appare nelle tipologie: | 1.1 Articolo in Rivista |
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