Considerable progress in the synthesis and technology of hydrogels makes these materials attractive structures for designing controlled-release drug delivery systems. In particular, this review highlights the latest advances in nanocomposite hydrogels as drug delivery vehicles. The inclusion/incorporation of nanoparticles in three-dimensional polymeric structures is an innovative means for obtaining multicomponent systems with diverse functionality within a hybrid hydrogel network. Nanoparticle-hydrogel combinations add synergistic benefits to the new 3D structures. Nanogels as carriers for cancer therapy and injectable gels with improved self-healing properties have also been described as new nanocomposite systems.
Titolo: | Nanocomposite hydrogels: 3D polymer-nanoparticle synergies for on-demand drug delivery |
Autori: | |
Data di pubblicazione: | 2015 |
Rivista: | |
Abstract: | Considerable progress in the synthesis and technology of hydrogels makes these materials attractive structures for designing controlled-release drug delivery systems. In particular, this review highlights the latest advances in nanocomposite hydrogels as drug delivery vehicles. The inclusion/incorporation of nanoparticles in three-dimensional polymeric structures is an innovative means for obtaining multicomponent systems with diverse functionality within a hybrid hydrogel network. Nanoparticle-hydrogel combinations add synergistic benefits to the new 3D structures. Nanogels as carriers for cancer therapy and injectable gels with improved self-healing properties have also been described as new nanocomposite systems. |
Handle: | http://hdl.handle.net/11368/2849613 |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1021/acsnano.5b01433 |
URL: | http://pubs.acs.org/journal/ancac3 |
Appare nelle tipologie: | 1.1 Articolo in Rivista |
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