A simple laboratory procedure for the isolation of pure cafestol and 16-O-methylcafestol together with beta-sitosterol from coffee is disclosed. Cafestol and 16-O-methylcafestol have been exhaustively characterized through 1D and 2D H-1, C-13 NMR, CD and X-ray diffraction. For the first time, the molecular structure of cafestol is reported and the assignment of the absolute configuration is unequivocally given by exploiting anomalous scattering of a brominated derivative.

Isolation and characterization of major diterpenes from C. canephora roasted coffee oil

GUERCIA, ELENA;BERTI, FEDERICO;DEMITRI, NICOLA;FORZATO, Cristina
2016

Abstract

A simple laboratory procedure for the isolation of pure cafestol and 16-O-methylcafestol together with beta-sitosterol from coffee is disclosed. Cafestol and 16-O-methylcafestol have been exhaustively characterized through 1D and 2D H-1, C-13 NMR, CD and X-ray diffraction. For the first time, the molecular structure of cafestol is reported and the assignment of the absolute configuration is unequivocally given by exploiting anomalous scattering of a brominated derivative.
http://www.journals.elsevier.com/tetrahedron-asymmetry/
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11368/2882463
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