The synthesis of the first examples of calix[4]arene-based Fischer carbene complexes is reported here. Fischer carbene complex 2 is the key intermediate to reach uracil-like derivatives 3 and 4. X-ray and NMR studies revealed that the uracyl-like synthon gives rise to a supramolecular dimer. The organometallic calixarene complexes showed a promising cytotoxicity towards human tumor cell lines.

Installing tungsten Fischer carbene complexes into a calixarene framework

BRANCATELLI, GIOVANNA;GEREMIA, SILVANO;
2016

Abstract

The synthesis of the first examples of calix[4]arene-based Fischer carbene complexes is reported here. Fischer carbene complex 2 is the key intermediate to reach uracil-like derivatives 3 and 4. X-ray and NMR studies revealed that the uracyl-like synthon gives rise to a supramolecular dimer. The organometallic calixarene complexes showed a promising cytotoxicity towards human tumor cell lines.
http://pubs.rsc.org/en/Content/ArticleLanding/2016/RA/C6RA17326H#!divAbstract
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11368/2889708
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