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EnglishIn this work, hydrogen peroxide (H2O2) was employed to improve the adhesion of an alginate-based membrane to intestinal serosa: mechanical adhesion test and SEC-MALLS studies were performed to investigate the contribution of H2O2-induced modifications of both tissue and membrane to the adhesion enhancement. Adhesion tests confirmed that the formation of an adhesive gelatin layer on serosa plays a major role in increasing adhesion forces, while SEC-MALLS studies revealed a slight decrease of alginate molecular weight. However, the latter chain degradation does not seem to significantly impair the adhesion strength. Overall, this study describes a possible strategy to create adhesive interfaces between biomaterials and collagen-containing tissues
| Titolo: | H2O2 Causes Improved Adhesion Between a Polysaccharide-based Membrane and Intestinal Serosa |
| Autori: | |
| Data di pubblicazione: | 2016 |
| Rivista: | |
| Abstract: | In this work, hydrogen peroxide (H2O2) was employed to improve the adhesion of an alginate-based membrane to intestinal serosa: mechanical adhesion test and SEC-MALLS studies were performed to investigate the contribution of H2O2-induced modifications of both tissue and membrane to the adhesion enhancement. Adhesion tests confirmed that the formation of an adhesive gelatin layer on serosa plays a major role in increasing adhesion forces, while SEC-MALLS studies revealed a slight decrease of alginate molecular weight. However, the latter chain degradation does not seem to significantly impair the adhesion strength. Overall, this study describes a possible strategy to create adhesive interfaces between biomaterials and collagen-containing tissues |
| Handle: | http://hdl.handle.net/11368/2891985 |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.colcom.2016.11.002 |
| URL: | http://www.sciencedirect.com/science/journal/22150382/15 |
| Appare nelle tipologie: | 1.1 Articolo in Rivista |
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http://hdl.handle.net/11368/2891985
