HIV-1 virus is known to infect the host mainly through CD4+ T-lymphocyte cells, by interactions among the viral envelope proteins, CD4 receptor and HIV-1 coreceptors, such as chemokines receptors. Variations in the genes encoding HIV-1 coreceptors and their natural ligands have been shown to modify HIV-1 infection susceptibility and disease progression.



Titolo: Chemokines SNPs in HIV-1+ Patients and Healthy Controls from Northeast Brazil: Association with Protection against HIV-1 Infection
Autori: 
CROVELLA, SERGIO
mostra contributor esterni 
Data di pubblicazione: 2016
Rivista: 
CURRENT HIV RESEARCH  
Abstract: HIV-1 virus is known to infect the host mainly through CD4+ T-lymphocyte cells, by interactions among the viral envelope proteins, CD4 receptor and HIV-1 coreceptors, such as chemokines receptors. Variations in the genes encoding HIV-1 coreceptors and their natural ligands have been shown to modify HIV-1 infection susceptibility and disease progression.
Handle: http://hdl.handle.net/11368/2894011
Digital Object Identifier (DOI): 10.2174/1570162X14666160120152237
URL: http://www.eurekaselect.com/138586/article
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