HIV-1 virus is known to infect the host mainly through CD4+ T-lymphocyte cells, by interactions among the viral envelope proteins, CD4 receptor and HIV-1 coreceptors, such as chemokines receptors. Variations in the genes encoding HIV-1 coreceptors and their natural ligands have been shown to modify HIV-1 infection susceptibility and disease progression.
Chemokines SNPs in HIV-1+ Patients and Healthy Controls from Northeast Brazil: Association with Protection against HIV-1 Infection / Celerino da Silva, Ronaldo; Victor Campos Coelho, Antonio; Cláudio Arraes, Luiz; André Cavalcanti Brandão, Lucas; Lima Guimarães, Rafael; Crovella, Sergio. - In: CURRENT HIV RESEARCH. - ISSN 1873-4251. - 14:4(2016), pp. 340-345. [10.2174/1570162X14666160120152237]
Chemokines SNPs in HIV-1+ Patients and Healthy Controls from Northeast Brazil: Association with Protection against HIV-1 Infection
CROVELLA, SERGIO
2016-01-01
Abstract
HIV-1 virus is known to infect the host mainly through CD4+ T-lymphocyte cells, by interactions among the viral envelope proteins, CD4 receptor and HIV-1 coreceptors, such as chemokines receptors. Variations in the genes encoding HIV-1 coreceptors and their natural ligands have been shown to modify HIV-1 infection susceptibility and disease progression.| File | Dimensione | Formato | |
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Chemockines_SNPs_Curr_HIV_def.pdf
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