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EnglishThe serum anti-transglutaminase antibodies are the immunological markers for coeliac disease diagnosis. These autoantibodies are synthesized by B-lymphocytes at the intestinal level and their presence in the form of intestinal deposits is a constant feature in the different clinical entities in which coeliac disease is classified: classical, silent, and potential. These intestinal autoantibodies are the first gluten dependent inflammatory markers and they appear before both the intestinal damage and the serum anti-transglutaminase antibodies. The anti-transglutaminase deposits should be looked for to confirm or exclude the diagnosis of coeliac disease when the clinical and immunological features are incomplete or in asymptomatic at risk patients.
| Titolo: | I depositi intestinali degli anticorpi anti-transglutaminasi: Il marcatore più sensibile per la diagnosi di celiachia nei casi difficili | |
| Autori: | ||
| Data di pubblicazione: | 2016 | |
| Stato di pubblicazione: | Pubblicato | |
| Rivista: | ||
| Abstract: | The serum anti-transglutaminase antibodies are the immunological markers for coeliac disease diagnosis. These autoantibodies are synthesized by B-lymphocytes at the intestinal level and their presence in the form of intestinal deposits is a constant feature in the different clinical entities in which coeliac disease is classified: classical, silent, and potential. These intestinal autoantibodies are the first gluten dependent inflammatory markers and they appear before both the intestinal damage and the serum anti-transglutaminase antibodies. The anti-transglutaminase deposits should be looked for to confirm or exclude the diagnosis of coeliac disease when the clinical and immunological features are incomplete or in asymptomatic at risk patients. | |
| Handle: | http://hdl.handle.net/11368/2896455 | |
| URL: | http://www.medicoebambino.com/?id=1603_159.pdf | |
| Appare nelle tipologie: | 1.1 Articolo in Rivista |
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