The serum anti-transglutaminase antibodies are the immunological markers for coeliac disease diagnosis. These autoantibodies are synthesized by B-lymphocytes at the intestinal level and their presence in the form of intestinal deposits is a constant feature in the different clinical entities in which coeliac disease is classified: classical, silent, and potential. These intestinal autoantibodies are the first gluten dependent inflammatory markers and they appear before both the intestinal damage and the serum anti-transglutaminase antibodies. The anti-transglutaminase deposits should be looked for to confirm or exclude the diagnosis of coeliac disease when the clinical and immunological features are incomplete or in asymptomatic at risk patients.
Titolo: | I depositi intestinali degli anticorpi anti-transglutaminasi: Il marcatore più sensibile per la diagnosi di celiachia nei casi difficili | |
Autori: | ||
Data di pubblicazione: | 2016 | |
Stato di pubblicazione: | Pubblicato | |
Rivista: | ||
Abstract: | The serum anti-transglutaminase antibodies are the immunological markers for coeliac disease diagnosis. These autoantibodies are synthesized by B-lymphocytes at the intestinal level and their presence in the form of intestinal deposits is a constant feature in the different clinical entities in which coeliac disease is classified: classical, silent, and potential. These intestinal autoantibodies are the first gluten dependent inflammatory markers and they appear before both the intestinal damage and the serum anti-transglutaminase antibodies. The anti-transglutaminase deposits should be looked for to confirm or exclude the diagnosis of coeliac disease when the clinical and immunological features are incomplete or in asymptomatic at risk patients. | |
Handle: | http://hdl.handle.net/11368/2896455 | |
URL: | http://www.medicoebambino.com/?id=1603_159.pdf | |
Appare nelle tipologie: | 1.1 Articolo in Rivista |
File in questo prodotto:
File | Descrizione | Tipologia | Licenza | |
---|---|---|---|---|
MedicoeBambino_1603_159(1)-16-18.pdf | Documento in Versione Editoriale | Digital Rights Management non definito | Administrator Richiedi una copia |