Tuning molecular structures of self-assembling multivalent (SAMul) dendritic cationic lipopeptides controls the self-assembled morphology. In buffer, spherical micelles formed by higher generation systems bind polyanionic heparin better than worm-like micelles formed by lower generation systems. In human serum, the binding of spherical micelles to heparin is adversely affected, while worm-like micelles maintain their relative binding ability.
Titolo: | Morphological control of self-assembled multivalent (SAMul) heparin binding in highly competitive media | |
Autori: | ||
Data di pubblicazione: | 2017 | |
Stato di pubblicazione: | Pubblicato | |
Rivista: | ||
Abstract: | Tuning molecular structures of self-assembling multivalent (SAMul) dendritic cationic lipopeptides controls the self-assembled morphology. In buffer, spherical micelles formed by higher generation systems bind polyanionic heparin better than worm-like micelles formed by lower generation systems. In human serum, the binding of spherical micelles to heparin is adversely affected, while worm-like micelles maintain their relative binding ability. | |
Handle: | http://hdl.handle.net/11368/2904292 | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1039/C7CC02990J | |
URL: | http://pubs.rsc.org/en/Content/ArticleLanding/2017/CC/C7CC02990J#!divAbstract | |
Appare nelle tipologie: | 1.1 Articolo in Rivista |
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