We are intrigued by the report of Abraham et al.1 illustrating the case of a 4‐year‐old child with a histomorphologically atypical, but genetically normal (by array comparative genomic hybridization) melanocytic neoplasm, with deep penetrating nevus (DPN)‐like features. In a sentinel lymph node biopsy (SLNB), there were foci of tumor, which the authors considered as an evidence of a ‘metastatic’ melanocytic tumor, of uncertain malignant potential (MelTUMP). Interestingly, the very same case was interpreted by McCalmont and Bastian2 in a ‘counter perspective’ as representing an ‘unconventional’ DPN with microscopic involvement of the SLNB.
Melanocytic tumors of uncertain malignant potential in childhood: do we really need sentinel node biopsy?
Zalaudek, Iris
;
2012-01-01
Abstract
We are intrigued by the report of Abraham et al.1 illustrating the case of a 4‐year‐old child with a histomorphologically atypical, but genetically normal (by array comparative genomic hybridization) melanocytic neoplasm, with deep penetrating nevus (DPN)‐like features. In a sentinel lymph node biopsy (SLNB), there were foci of tumor, which the authors considered as an evidence of a ‘metastatic’ melanocytic tumor, of uncertain malignant potential (MelTUMP). Interestingly, the very same case was interpreted by McCalmont and Bastian2 in a ‘counter perspective’ as representing an ‘unconventional’ DPN with microscopic involvement of the SLNB.Pubblicazioni consigliate
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