Cleft formation is thought to be a retraction artefact observed in histopathology due to formalin fixation dehydration. However, cleft-like retraction spaces between intraepidermal nests of melanocytes and adjacent epidermis are observed on histopathology more frequently in Spitz/Reed naevi and melanomas than in other melanocytic proliferations.

In vivo detection of peripheral clefting in melanocytic lesions / Benati, E., Zalaudek, I., Piana, S., Argenziano, G., Moscarella, E., Lallas, A., Pellacani, G., Longo, C.. - In: BRITISH JOURNAL OF DERMATOLOGY. - ISSN 0007-0963. - 173:6(2015), pp. 1525-1526. [10.1111/bjd.13959]

In vivo detection of peripheral clefting in melanocytic lesions

Zalaudek, I.
;
2015-01-01

Abstract

Cleft formation is thought to be a retraction artefact observed in histopathology due to formalin fixation dehydration. However, cleft-like retraction spaces between intraepidermal nests of melanocytes and adjacent epidermis are observed on histopathology more frequently in Spitz/Reed naevi and melanomas than in other melanocytic proliferations.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2923343
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