Genome-wide association studies conducted on QRS duration, an electrocardiographic measurement associated with heart failure and sudden cardiac death, have led to novel biological insights into cardiac function. However, the variants identified fall predominantly in non-coding regions and their underlying mechanisms remain unclear.

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Cappellani, Stefania;Iorio, Annamaria;Robino, Antonietta;Gasparini, Paolo;Sinagra, Gianfranco;Ulivi, Sheila;
2018-01-01

Abstract

Genome-wide association studies conducted on QRS duration, an electrocardiographic measurement associated with heart failure and sudden cardiac death, have led to novel biological insights into cardiac function. However, the variants identified fall predominantly in non-coding regions and their underlying mechanisms remain unclear.
2018
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https://genomebiology.biomedcentral.com/articles/10.1186/s13059-018-1457-6
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2929017
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