In this study we demonstrate the efficacy of VEGF 165 delivered by an Adeno-Associated Virus (AAV) vector in rat flap models. In the rectus abdominis myocutaneous flap, intramuscular injection of AAV-VEGF reduced flap necrosis, while cutaneous delivery of the same amount of vector put down the epigastric flap's ischemia.
IMPROVED SURVIVAL AND VASCULARIZATION OF ISCHEMIC CUTANEOUS AND MUSCULOCUTANEOUS FLAPS AFTER AAV-VEGF165 GENE TRANSFER
Zacchigna S;Papa G;Giacca M
2003-01-01
Abstract
In this study we demonstrate the efficacy of VEGF 165 delivered by an Adeno-Associated Virus (AAV) vector in rat flap models. In the rectus abdominis myocutaneous flap, intramuscular injection of AAV-VEGF reduced flap necrosis, while cutaneous delivery of the same amount of vector put down the epigastric flap's ischemia.File in questo prodotto:
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