A series of multinuclear heterometallic Cu−Zn complexes of molecular formula [(CuL)2Zn(dca)2] (1), [(CuL)2Zn(NO3)2] (2), [(CuL)2Zn2(Cl)4] (3), and [(CuL)2Zn2(NO2)4] (4) have been synthesized by reacting [CuL] as a “metalloligand (ML)” (where HL = N,N′-bis(5- chloro-2-hydroxybenzylidene)-2,2-dimethylpropane-1,3-diamine) and by varying the anions or coligands using the same molar ratios of the reactants. All of the four products including the ML have been characterized by infrared and UV−vis spectroscopies and elemental and single-crystal X-ray diffraction analyses. By varying the anions, different structures and topologies are obtained which we have tried to rationalize by means of thorough density functional theory calculations. All of the complexes (1−4) have now been applied for several biological investigations to verify their therapeutic worth.

Bioactive Heterometallic CuII-ZnII Complexes with Potential Biomedical Applications

Zangrando, Ennio;
2018-01-01

Abstract

A series of multinuclear heterometallic Cu−Zn complexes of molecular formula [(CuL)2Zn(dca)2] (1), [(CuL)2Zn(NO3)2] (2), [(CuL)2Zn2(Cl)4] (3), and [(CuL)2Zn2(NO2)4] (4) have been synthesized by reacting [CuL] as a “metalloligand (ML)” (where HL = N,N′-bis(5- chloro-2-hydroxybenzylidene)-2,2-dimethylpropane-1,3-diamine) and by varying the anions or coligands using the same molar ratios of the reactants. All of the four products including the ML have been characterized by infrared and UV−vis spectroscopies and elemental and single-crystal X-ray diffraction analyses. By varying the anions, different structures and topologies are obtained which we have tried to rationalize by means of thorough density functional theory calculations. All of the complexes (1−4) have now been applied for several biological investigations to verify their therapeutic worth.
File in questo prodotto:
File Dimensione Formato  
acsomega.8b01260.pdf

accesso aperto

Descrizione: ACS AuthorChoice https://pubs.acs.org/page/4authors/authorchoice/index.html
Tipologia: Documento in Versione Editoriale
Licenza: Copyright Editore
Dimensione 3.94 MB
Formato Adobe PDF
3.94 MB Adobe PDF Visualizza/Apri
ao8b01260_si_001.pdf

accesso aperto

Descrizione: Supporting information - ACS AuthorChoice https://pubs.acs.org/page/4authors/authorchoice/index.html
Tipologia: Altro materiale allegato
Licenza: Copyright Editore
Dimensione 1.18 MB
Formato Adobe PDF
1.18 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2940111
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 8
  • ???jsp.display-item.citation.isi??? 8
social impact