This study aimed at re-evaluating the strength and shape of the dose-response relationship between the combined (or joint) effect of intensity and duration of cigarette smoking and the risk of head and neck cancer (HNC). We explored this issue considering bivariate spline models, where smoking intensity and duration were treated as interacting continuous exposures.

Joint effects of intensity and duration of cigarette smoking on the risk of head and neck cancer: A bivariate spline model approach

Di Credico, Gioia;Pauli, Francesco;Torelli, Nicola;
2019-01-01

Abstract

This study aimed at re-evaluating the strength and shape of the dose-response relationship between the combined (or joint) effect of intensity and duration of cigarette smoking and the risk of head and neck cancer (HNC). We explored this issue considering bivariate spline models, where smoking intensity and duration were treated as interacting continuous exposures.
2019
17-mag-2019
Pubblicato
https://www.sciencedirect.com/science/article/pii/S1368837519301447
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2944237
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