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EnglishWe fully agree with the authors that there is lack of validated histopathological criteria that allow to accurately differentiate well-differentiated SCC from KA. For this reason, we believe that both terms should be best avoided in the future. Therefore, we recently proposed a novel classification system, which simply differentiates whether the tumors arise within a field of cancerization and or in the absence of field cancerization. [2] We consider the former as true carcinomas with a low but existing metastatic potential.
| Titolo: | Comment on 'The detection rate of Human Papillomavirus (HPV) in well differentiated squamous cell carcinoma and keratoacanthoma: is there new evidence for a viral pathogenesis of keratoacanthoma?' - Reply from authors. |
| Autori: | ZALAUDEK, IRIS (Corresponding) |
| Data di pubblicazione: | 2019 |
| Data ahead of print: | 2-ago-2019 |
| Stato di pubblicazione: | Pubblicato |
| Rivista: | |
| Abstract: | We fully agree with the authors that there is lack of validated histopathological criteria that allow to accurately differentiate well-differentiated SCC from KA. For this reason, we believe that both terms should be best avoided in the future. Therefore, we recently proposed a novel classification system, which simply differentiates whether the tumors arise within a field of cancerization and or in the absence of field cancerization. [2] We consider the former as true carcinomas with a low but existing metastatic potential. |
| Handle: | http://hdl.handle.net/11368/2947509 |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1111/bjd.18385 |
| URL: | https://onlinelibrary.wiley.com/doi/full/10.1111/bjd.18385 |
| Appare nelle tipologie: | 1.1 Articolo in Rivista |
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