Hybridization of a chiral 3-hydroxy-2-trityl-pyrrolidine deriving from (R)-pyrrolidinol with [60] fullerene via click chemistry provides a highly efficient supported enantioselective organocatalyst, which was successfully exploited in a Michael addition of malonates to cinnamaldehydes, via iminium ion activation. The supported organocatalyst was recycled up to six times, with only a moderate decrease in terms of activity and with no loss in enantioselectivity.

A Recyclable Chiral 2-(Triphenylmethyl)pyrrolidine Organocatalyst Anchored to [60]Fullerene

Rosso C.
Membro del Collaboration Group
;
Syrgiannis Z.;Prato M.
2019-01-01

Abstract

Hybridization of a chiral 3-hydroxy-2-trityl-pyrrolidine deriving from (R)-pyrrolidinol with [60] fullerene via click chemistry provides a highly efficient supported enantioselective organocatalyst, which was successfully exploited in a Michael addition of malonates to cinnamaldehydes, via iminium ion activation. The supported organocatalyst was recycled up to six times, with only a moderate decrease in terms of activity and with no loss in enantioselectivity.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2948210
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