Apolipoprotein L1 gene (APOL1) G1 and G2 renal-risk alleles (RRAs) are associated with end-stage renal disease (ESRD) in blacks with lupus nephritis (LN). The present study determined frequencies of APOL1 RRAs in non-white Brazilian patients with LN and controls to assess association with renal outcomes.
Effect of a Single Apolipoprotein L1 Gene Nephropathy Variant on the Risk of Advanced Lupus Nephritis in Brazilians / Vajgel, Gisele; Lima, Suelen Cristina; Santana, Diego Jeronimo S; Oliveira, Camila B L; Costa, Denise Maria N; Hicks, Pamela J; Cavalcante, Maria Alina G M; Langefeld, Carl D; Valente, Lucila Maria; Crovella, Sergio; Kirsztajn, Gianna Mastroianni; Freedman, Barry I; Sandrin-Garcia, Paula. - In: THE JOURNAL OF RHEUMATOLOGY. - ISSN 0315-162X. - STAMPA. - 47:8(2020), pp. 1209-1217. [10.3899/jrheum.190684]
Effect of a Single Apolipoprotein L1 Gene Nephropathy Variant on the Risk of Advanced Lupus Nephritis in Brazilians
Crovella, Sergio;
2020-01-01
Abstract
Apolipoprotein L1 gene (APOL1) G1 and G2 renal-risk alleles (RRAs) are associated with end-stage renal disease (ESRD) in blacks with lupus nephritis (LN). The present study determined frequencies of APOL1 RRAs in non-white Brazilian patients with LN and controls to assess association with renal outcomes.| File | Dimensione | Formato | |
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APO1_nephropathy_SLE_jrheum.pdf
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Alipoprotein-Crovella.pdf
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