Apolipoprotein L1 gene (APOL1) G1 and G2 renal-risk alleles (RRAs) are associated with end-stage renal disease (ESRD) in blacks with lupus nephritis (LN). The present study determined frequencies of APOL1 RRAs in non-white Brazilian patients with LN and controls to assess association with renal outcomes.
Effect of a Single Apolipoprotein L1 Gene Nephropathy Variant on the Risk of Advanced Lupus Nephritis in Brazilians / Vajgel, G., Lima, S.C., Santana, D.J.S., Oliveira, C.B.L., Costa, D.M.N., Hicks, P.J., Cavalcante, M.A.G.M., Langefeld, C.D., Valente, L.M., Crovella, S., Kirsztajn, G.M., Freedman, B.I., Sandrin-Garcia, P.. - In: THE JOURNAL OF RHEUMATOLOGY. - ISSN 0315-162X. - STAMPA. - 47:8(2020), pp. 1209-1217. [10.3899/jrheum.190684]
Effect of a Single Apolipoprotein L1 Gene Nephropathy Variant on the Risk of Advanced Lupus Nephritis in Brazilians
Crovella, Sergio;
2020-01-01
Abstract
Apolipoprotein L1 gene (APOL1) G1 and G2 renal-risk alleles (RRAs) are associated with end-stage renal disease (ESRD) in blacks with lupus nephritis (LN). The present study determined frequencies of APOL1 RRAs in non-white Brazilian patients with LN and controls to assess association with renal outcomes.| File | Dimensione | Formato | |
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APO1_nephropathy_SLE_jrheum.pdf
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Alipoprotein-Crovella.pdf
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