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EnglishThe uncapped tripeptide DPhe-Phe-Leu acts as self-assembly template to yield supramolecular hydrogel biomaterials. As an example, self-assembling DPhe-Phe-Leu-Asp-Val contains the LDV bioadhesive motif for β1 integrin activation. Hydrogels made of the two peptides successfully mimic fibronectin of the extracellular matrix and lead to high cell viability, adhesion, and spreading.
| Titolo: | Bioadhesive supramolecular hydrogel from unprotected, short d,l-peptides with Phe-Phe and Leu-Asp-Val motifs |
| Autori: | MARCHESAN, SILVIA (Corresponding) |
| Data di pubblicazione: | 2020 |
| Stato di pubblicazione: | Pubblicato |
| Rivista: | |
| Abstract: | The uncapped tripeptide DPhe-Phe-Leu acts as self-assembly template to yield supramolecular hydrogel biomaterials. As an example, self-assembling DPhe-Phe-Leu-Asp-Val contains the LDV bioadhesive motif for β1 integrin activation. Hydrogels made of the two peptides successfully mimic fibronectin of the extracellular matrix and lead to high cell viability, adhesion, and spreading. |
| Handle: | http://hdl.handle.net/11368/2969082 |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1039/c9cc09947f |
| URL: | https://pubs.rsc.org/en/content/articlelanding/2020/CC/C9CC09947F#!divAbstract |
| Appare nelle tipologie: | 1.1 Articolo in Rivista |
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| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| Cringoli_CC_postprint.pdf | Bozza finale post-referaggio (post-print) | Copyright Editore | Open Access Visualizza/Apri |
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