An aberrant and persistent inflammatory state at the fetal-maternal interface is considered as a key contributor in compromised pregnancies. Decidual endothelial cells (DECs) play a pivotal role in the control of the local decidual inflammation. The aim of the current study was to determine whether dietary supplement with zinc oxide (ZnO), due to its very low adverse effects, may be useful for modulating the inflammatory response in the first trimester of pregnancy.
Zinc Oxide Exerts Anti-Inflammatory Properties on Human Placental Cells
Balduit, Andrea;Mangogna, Alessandro;Agostinis, Chiara
;Zito, Gabriella;Romano, Federico;Ricci, Giuseppe;Bulla, Roberta
2020-01-01
Abstract
An aberrant and persistent inflammatory state at the fetal-maternal interface is considered as a key contributor in compromised pregnancies. Decidual endothelial cells (DECs) play a pivotal role in the control of the local decidual inflammation. The aim of the current study was to determine whether dietary supplement with zinc oxide (ZnO), due to its very low adverse effects, may be useful for modulating the inflammatory response in the first trimester of pregnancy.File in questo prodotto:
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nutrients-12-01822-v2-1.pdf
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Descrizione: Supplementary material at link http://www.mdpi.com/2072-6643/12/6/1822/s1.
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