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EnglishCatanionic vesicles are emerging interesting structures for bioapplications. They selfgenerate by a pairing of oppositely charged ionic surfactants that assemble into hollow structures. Specifically, the anionic-cationic surfactant pair assumes a double-tailed zwitterionic behavior. In this work, the multilamellar-to-unilamellar thermal transition of several mixed aqueous systems, with a slight excess of the anionic one, were investigated. Interestingly, it was found that the anionic counterion underwent a dissociation as a consequence of a temperature increase, leading to the mentioned thermal transition. The present work proposed the spectroscopic techniques, specifically multinuclear NMR and PGSTE (pulsed gradient stimulated echo), as a key tool to study such systems, with high accuracy and effectiveness, while requiring a small amount of the sample. The results presented herein evidence encouraging perspectives, forecasting the application of the studied vesicular nanoreservoirs, for e.g., drug delivery.
| Titolo: | Soft nanoonions: A dynamic overview onto catanionic vesicles temperature-driven transition |
| Autori: | |
| Data di pubblicazione: | 2020 |
| Stato di pubblicazione: | Pubblicato |
| Rivista: | |
| Abstract: | Catanionic vesicles are emerging interesting structures for bioapplications. They selfgenerate by a pairing of oppositely charged ionic surfactants that assemble into hollow structures. Specifically, the anionic-cationic surfactant pair assumes a double-tailed zwitterionic behavior. In this work, the multilamellar-to-unilamellar thermal transition of several mixed aqueous systems, with a slight excess of the anionic one, were investigated. Interestingly, it was found that the anionic counterion underwent a dissociation as a consequence of a temperature increase, leading to the mentioned thermal transition. The present work proposed the spectroscopic techniques, specifically multinuclear NMR and PGSTE (pulsed gradient stimulated echo), as a key tool to study such systems, with high accuracy and effectiveness, while requiring a small amount of the sample. The results presented herein evidence encouraging perspectives, forecasting the application of the studied vesicular nanoreservoirs, for e.g., drug delivery. |
| Handle: | http://hdl.handle.net/11368/2977711 |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.3390/ijms21186804 |
| URL: | https://www.mdpi.com/1422-0067/21/18/6804 |
| Appare nelle tipologie: | 1.1 Articolo in Rivista |
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| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| IJMS 2020.pdf | Documento in Versione Editoriale |  | Open Access Visualizza/Apri |
